Welcome! We regret to inform you that the Injury Board National News Desk has been discontinued. Feel free to browse around and enjoy our previously published articles, or visit The Injury Blog Network for the latest in personal injury news.

Skin Cancer Cream Fights Wrinkles

Posted by Chrissie Cole
Tuesday, June 16, 2009 3:10 PM EST
Category: Major Medical
Tags: FDA and Prescription Drugs, Fluorouracil, Skin Cancer, Efudex, Squamous Cell Carcinoma

LEARN MORE

IMAGE SOURCE: Efudex / Valeant Pharmaceuticals

A cream used to treat the early signs of skin cancer may also reverse signs of aging leaving behind younger-looking skin, a small study in the Archives of Dermatology, reveals.

Fluorouracil (brand name Efudex), made by Valeant Pharmaceuticals, is a skin treatment used to treat actinic keratoses, pre-cancerous lesions caused by sun damage.

The cream works by causing damage to skin cells, forcing the body to rebuild them, in much the same way as laser treatment, according to Dr. Dana L. Sachs, M.D., of the University of Michigan.

For the study, researchers studied 21 patients with actinic keratoses and sun damage. Twice a day for two weeks, they applied a 5% fluorouracil skin cream to their face. The team measured changes in the skin, taking facial biopsies over a six-month period.

During the first phase, the patients’ facial skin got dry, itchy and then peeled. In the weeks after, their skin recovered with softer wrinkles and texture.

Generally all patients reported mild improvement in their skin texture. Overall, 75% of the patients were “very” or “moderately” satisfied with the results.

One patient stopped using the cream in the first week because his skin became severely inflamed.

While most patients said they found the treatment to be “moderately” uncomfortable, they said they would be willing to get the treatment again. They also said they would pay out of pocket for it.

Actinic keratoses (AK), also known as a solar keratosis, are small, rough spots caused by years of sun damage and can lead to squamous cell carcinoma, one of the two most common types of skin cancer that represents more than 1 million cases each year. These types of cancer are highly treatable but can be fatal if neglected.

Fluorouracil treatment can be a useful treatment for precancerous skin changes, but the risk of severe reaction will likely put off most people looking for a solution to cosmetic concerns, note researchers.

They further add the best way to avoid wrinkles is to avoid too much exposure to the sun. #


1 Comment

Posted by edwards
Tuesday, June 16, 2009 4:24 PM EST

The potential of fluorouracil cream (fluorouracilcream.com) is extraordinary. Given the size of the anti-aging, wrinkle-removal product sales, in the U.S. and worldwide (over $12 billion in 2005 according to The American Society for Aesthetic Plastic Surgery), this substance could become a blockbuster.

Comments for this article are closed.

About the National News Desk

Our mission is to seek the complete truth and provide a full and fair account of the events and issues that surround personal safety, accident prevention, and injury recovery.  We are committed to serving the public with honesty and integrity in these efforts.

Hurt in an accident? Contact an Injury Board member

Subscribe to Blog Updates

Enter your email address if you would like to receive email notifications when comments are made on this post.

Email address

Subscribe

RSS Feed

Add the National News Desk to your favorite RSS reader

Add to Google Reader Add to myYahoo Add to myMSN Add to Bloglines Add to Newsgator Add to Netvibes Add to Pageflakes