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OxyContin Maker Says New Formula Offers Less Chance of Abuse

Posted by Jane Akre
Wednesday, September 23, 2009 12:37 PM EST
Category: Major Medical
Tags: Painkiller, Prescription Medication, OxyContin, Oxycondone, Narcotics, Rush Limbaugh, FDA

OxyContin is abused by addicts. Drug maker is asking the FDA to reformulate it so there is less chance for abuse.




IMAGE SOURCE: A Mothers Against Medical Abuse Web site/ billboard honoring Elliott Matos who died from OxyContin


The maker of the painkiller, OxyContin has applied to the Food and Drug Administration to reformulate the pill to reduce the chances of misuse or abuse.

Purdue Pharma LP wants the drug to be tamper-resistant so it’s harder to crush and dissolve in water. The active drug would be released as a gel making it harder to inject, according the FDA staff reporting on the agency’s Web site.

Drug abusers typically dissolve or crush the drug and put it in water to inject it for a heroin-like effect.

Two years ago, the company had to pay $635 million to settle federal charges that it underplayed the drug’s potential for abuse. Addiction rates are reported to be between 1 and 13 percent.

Purdue is in a race with King Pharmaceuticals Inc, which is reformulating oxycodone, the active drug in OxyContin. Outside advisors will meet on the application Thursday.

Last year the FDA refused a request to reformulate OxyContin, saying there was not enough information on the new version. This time around Purdue will leave out information about the tamper-resistant qualities in the product’s label, reports the Wall Street Journal.

OxyContin was approved by the FDA in 1995 to treat chronic pain. Radio host, Rush Limbaugh admitted an addiction to the drug in 2003, and sought treatment, narrowly averting felony charges for doctor shopping.

If approved, Purdue, of Stamford, Conn. will replace existing supplies with the new OxyContin-TR formula.

A report issued last year,  Monitoring the Future: National Results on Adolescent Drug Use, finds that marijuana and alcohol use has declined while the abuse of painkillers such as Vicodin and Oxycontin has increased among teens.

Much of the drug use among the young is seen in white middle-class families.  #


Posted by Marianne Skolek
Wednesday, September 23, 2009 3:48 PM EST

The convicted felons, Purdue Pharma now has a conscience and wants to reformulate OxyContin to be less likely to be abused. Give me a break. They marketed OxyContin to physicians and patients as less likely to be addictive or abused — were charged in Federal Court and pled guilty. Their actions are responsible for an epidemic of OxyContin death and addiction in every state in the country as well as Canada. There is a special place in hell for them.

Marianne Skolek
National Activist for Victims of OxyContin and
Purdue Pharma, a criminally convicted pharmaceutical company

Anonymous User
Posted by Clyde L. Horne
Thursday, September 24, 2009 11:20 AM EST

I think oxycontin should be banned. It has destroyed so many young lives. How can anyone with a conscience condone this company and their
practices of distribution. It has destroyed not only families but communities.

Anonymous User
Posted by Clyde L. Horne
Thursday, September 24, 2009 11:20 AM EST

I think oxycontin should be banned. It has destroyed so many young lives. How can anyone with a conscience condone this company and their
practices of distribution. It has destroyed not only families but communities.

Anonymous User
Posted by Sandra Scanlon
Saturday, October 03, 2009 1:24 PM EST

Another young person is addicted to this horrible FDA approved drug, and that young person is my son. Nice that Purdue Pharma is now re-formulating their killer drug. Maybe they should have done a lot more research on the long term
affects on peoples lives, instead of just their pocket book. I will be contacting anyone I can think of to try to get rid of this highly addictive and abused drug! My son is in treatment for the abuse of OXYCONTIN. This is definitely a social problem now, as young people are robbing pharmacies to get a hold of this drug.
Please use common sense when formulating these drugs...don't just look at your company bottom line. You do have a responsibility to the consumers, as was shown by your huge fine for falsely marketing the product in the beginning,
which is a drop in the bucket, considering the negative affects your drug has caused to many, many, lives. MAKE SURE YOU DO YOUR RESEARCH NEXT TIME!

Posted by Anonymous
Monday, October 12, 2009 1:01 AM EST

Let's be really careful about advances such as this. Who is say to that an individual won't just take more and more of the drug to achieve the same "high" that they would with OxyContin made using the same formula as before?

I would rather see us focus on teen education and drug rehab as means of combating addiction to this incredibly dangerous prescription drug.

Anonymous User
Posted by h
Tuesday, October 13, 2009 7:39 PM EST

Hello, i totaly understand what younger our generaton go through and people and by no means condone or approve of any addiction. I my self have had a severe back injury and have been on this drug for over 16 years and with the painful epidurals i get every three months,the doctors have made my pain maanagble. i take it like i am suppose to and never once have abused it. there are no high affects if taken properly either. i think this company should be commended for comming up with a pain medication that doesnt get you high,if taken properly. I am a drug and alcohol counselor and see the abuse from these younger people and totaly understand the frustration and concern,but before beating up these companies you realy should research and see the good this medication does. quit pointing fingers and look at all the drugs people have chose to abuse over all the centuries of mankind. This is not meant to be negative or condoning in any way as thats not my intent,but did want to express the good it has done for me.I personaly dont know the affects of the withdrawels that people go through,but sure i will one day.This can deep real quick and i better stop for now.

Anonymous User
Posted by chris OC gave me my life back
Friday, October 23, 2009 4:49 PM EST

The people who choose to abuse the drug get/got what they deserve. No body accidentally takes Oxycontin to get a high. They know their playing with fire and when they get burned they cry "its not fair" or "PurDue is the bad guy". Give me an F'ing break.
OC is the only drug that allows me to live a some what normal life after multiple back surgeries. Everyone knows the risks and except them when they take the drug. I have become physically dependent "addicted" to the drug but its worth it to me not to spend the rest of my life in bed screaming in pain. People abuse and die from alcohol all the time. Alcohol has no medical benefit yet nobody is crying to take vodka off the self. Alcohol, unlike Oxycontin doesn't require a doctors visit or a drug dealer either.
Anyone who blames Oxycontin on their problems needs to shut up and man up to their own responsibility's. It says all over the bottle and paper work that it can be "habit forming" so their is no mystery about the consequences of taking the drug.
Anyone NOT in chronic pain has to break the law to obtain the drug. That in its self should alert the person to its potential dangers. If Oxycontin is taken away or ruined it will leave thousands of chronic pain suffers like my self with a life not worth living. Don't let a few self destructive idiots ruin a very helpful drug for those who need it to live.
I am 27, since I was 24 I have relied on Oxycontin to be able to get out of bed much less live a productive life. My pain management doctor has a patient who is a drag racer and takes Oxycontin. Therefore in the correct dosage it does not hinder reaction time, coordination or any other ability to function.

Take away the only drug that thousands of us need to survive and you have doomed us all to a life of hellish pain. Other drugs like MS Contin and Morphine do not work as well and have horrible side effects for me and many others. That is why I am willing to pay $600/month for name brand OC verses morphine or MS Contin which would only cost me $10/month.
Worthless drug addicts are always going to be idiots and abuse whatever they can. Don't let their actions ruin the lives of those of us who just want to be productive people that don't have to live in a level of pain that would drive anyone to near suicide. The problem is NOT Oxycontin, the problem is the people who no matter what will find a way to abuse a substance. Blame them, not the drug.

Posted by CDAWG
Wednesday, November 18, 2009 3:57 AM EST


It is in no way Purdue's fault that your son is an oxycontin addict. He made the conscious decision to crush up that pill and snort it up his nose. Saying that it is Purdue's fault is like saying that it is God's fault for people addicted to smoking weed. If your son had a pair he could using this terrible drug instead of making excuses.

Comments for this article are closed.

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