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Crestor Maker Sees Sales Surge After Inflammation Study

Posted by Jane Akre
Tuesday, November 11, 2008 9:59 AM EST
Category: Major Medical, Protecting Your Family
Tags: Heart Disease, Stroke, Statins, Crestor, AstraZeneca, Lipitor, Baycol, Cholesterol Lowering Drugs

Crestor makers are seeing a jump in stock after release of a study on inflammation

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IMAGE SOURCE:© iStockphoto/ streaming blood/ author: Eraxion 

 

Doctors meeting this week at the American Heart Association’s annual gathering in New Orleans are talking about a new, simple, low-cost blood test that might be added to regular medical exams to assess heart disease.

Even when there are no outward symptoms of heart problems, the test detects a risk of heart disease and stroke risk and might indicate a patient should begin statin drugs.

That appears to be counterintuitive since the reason most drugs are prescribed is to counteract symptoms or disease.

“This kind of study probably will change cardiac practice,” said Dr. Deepak Srivastava, director of the Gladstone Institute of Cardiovascular Disease at UC San Francisco to the SF Chronicle.

 

The Test

The test does not measure artery plaque build-up but measures the amount of inflammation which can be associated with an increased risk of heart disease.

Known as CRP or C-reactive protein levels, the test costs about $20. It can indicate whether a patient has an intermediate risk for coronary artery events.

Statins work to reduce both inflammation and low-density or LDL cholesterol, also associated with coronary heart disease.

In the study presented at the cardiology conference,  patients taking Crestor for more than year, were 54 percent less likely to have a heart attack, 48 percent less likely to have a stroke, and 46 percent less likely to require angioplasty or bypass surgery.

Dr. John Kane, a professor of medicine at UCSF says, “It opens up a whole new group of people who probably ought to be treated. Before, if you came in for a routine physical in your 40s, no one would have measured your CRPs. Now this study says there’s a reason to measure it. It will lead to a change in guidelines for patients.”

 

Buyer Beware

Before you rush out and demand Crestor, be aware that the large study was financed by the pharmaceutical company that makes Crestor, AstraZeneca. 

Its stock rose Monday on news of the study which could open up the drug’s use to an entire new group of patients.

While those involved in the study say the company yielded no influence, appearances are everything.  The study also omitted people younger than their men in their 50s and women under 60.

Not completely free of controversy, the statin, Baycol was removed from the market in 2001 because of dangerous side effects.

Crestor, also known as rosuvastatin,  was approved in August 2003 and works by partially blocking the synthesis of cholesterol in the liver. Side effects include constipation, nausea, stomach pain and muscle aches. Statins have been associated with kidney damage.

Public Citizen in March 2004, called on the FDA to ban Crestor, citing the potential for kidney failure and muscle damage.

In the U.S. one person a minute dies from a coronary event.  Losing weight, not smoking and exercising are still the best ways to reduce your risk of heart problems and stroke.   

The Pauling Institute at Oregon State University, reports that a diet with high glycemic foods and trans fats stimulate inflammation. In contrast, a Mediterranean-style diet, rich in monounsaturated fatty acids such as olive oil, fruits and vegetables, nuts, beans and whole grains quiets inflammation.

The Food and Drug Administration must approve a change in the drug’s label before it can be more widely prescribed. #


2 Comments

Posted by DAWK
Tuesday, November 11, 2008 11:30 AM EST

IN ALL CAPS-FURIOUS: THIS KIND OF BIG PHARMA,OUTRIGHT (DANGEROUS DRUG STATIN)SCAMMING,USING THEIR CORRUPT-IN-BED-WITH THE FDA,WHO ARE ALSO GUILTY OF APPROVING THIS FATAL DRUG ,SHOULD BE BANNED FROM ANY-ALL FALSE PROMOTION.
THE ARTICLE DOES(POLITELY) REMIND READERS OF THE MANY DANGERS OF MUSCLE DAMAGE,AS THIS DAMAGE IS ...PERMANANT,NOT REVERSABLE,LET ALONE THE OTHER SIDE AFFECTS OF STATINS.AND OTHER NON BIG PHARMA STUDIES SAY THAT STATINNS DID NO BETTER THAN THE 'PLACEBOOS',BUT THEY NEVER 'HEADLINE' THIS IN THE NEWS SITES/PAPERS,BECAUSE THE MONEY ISN'T THERE FOR PROMOTION.
SEVERAL YEARS AGO, MY DOCTOR WANTED ME TO 'TAKE STATINS',SO I RESEARCHED IT FIRST AND FOUND THAT ANYONE WITH NERVE/MUSCLE PROBLEMS,WOULD SUCCUMB-SEVERLLY WITH WHEELCHAIR RESULTS,NO LONGER ABLE TO WALK!! I TOLD MY DOCTOR(I REFUSED TO TAKE IT,AS HE HAD NOT READ SUCH A STUDY,NOT INFORMED BY THE FDA YET) OF A FINDING IN EUROPE OF 500 DOCTORS,WHO BANNED-USE OF THIS STATIN DRUG,AND TWO YEARS LATER THE FDA WAS FORCED TO 'TAKE ACTION'. THE FDA HAS BECOME NOTHING BUT BIG PHARMA CRONIE ,AND SHOULD OF BANNED STATINS,LIKE EUROPE DID,BUT-NO....ALL THEY DID WAS TO PLACE A'STRONGER' WARNING ON THE LABEL.
FOLKS, IT HAS BEEN SEVERAL YEARS NOW,USING MY MEDITERAINAN DIET,WITH EXERCISE,SUPPLIMENTS,MINERALS,HERBS,AND AT AGE 68,MY HEART IS DOING FINE,WITH NO LIMB PARALISYS!!
CAN'T REMEMBER THE WORD? STATINS SOUND LIKE 'SATIN' AND RIGHTLY-SO,THEY ARE DEVILISH-EVIL,EXACTLY LIKE THE FDA AND BIG PHARMAA,SO GET-SMART,AND DO YOUR HOMEWORK,OR BIG PHARMA WILL LIKLEY GIVE YOU THE GIFT THAT KEEPS ON GIVING;THAT BE DRUG SIDE AFFECTS,WORSE THAN THE SO-CALLED 'EARLY DISEASE'!

Posted by susan allport
Wednesday, November 12, 2008 9:31 AM EST

Thought you would be interested in this short omega-3 video: LINK

Comments for this article are closed.

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